After five years at the top of the charts, the big-voiced superstar drew breath to look back at her incredible highs and devastating lows, including her 2003 breast cancer diagnosis.

Anastacia Lyn Newkirk was born into a show business family thanks to her singer father and her mother who worked in musical theatre on Broadway.

Having moved from Chicago to New York when she was a teenager, Anastacia joined the Professional Children's School in Manhattan.

The young Anastacia battled against Crohn's disease to develop a career in dance and can be spotted in the early Salt-N-Pepa videos ‘Everybody Get Up’ and ‘Twist and Shout’.

Having made it to the final of an MTV talent show in 1999, Anastacia succeeded in drawing attention to her unique voice from all the right places.

Signing up to an off-shoot of Epic records, she released her debut album ‘Not That Kind’ in 2000. Thanks to the worldwide hit ‘I'm Outta Love’, the album became an international bestseller, although success within the US would never match up to achievements abroad.

Her appearance alongside Shakira, Cher and Celine Dion for a VH1's Divas Live in 2002 helped awaken a US fan base and the 2002 release of 'Freak Of Nature' helped push her records sales passed the 20 million mark.

While her career was going from strength to strength, Anastacia discovered she had breast cancer in 2003 and underwent immediate treatment. Following a brief period of recovery, during which time she set up a Breast Cancer research fund, she returned to the studio to begin work on her self-titled ‘Anastacia’ album.

The first single to be lifted from the album, ‘Left Outside Alone’, showcased a rockier sound and the album topped the charts across Europe. However, the album was eventually denied a US release due a lack of airplay support from radio stations.

2005 saw a ‘Best Of’ compilation that rounded up all the hits alongside new tracks that included a duet with Italian heartthrob, Eros Ramazzotti. The DVD ‘Anastacia: Live at Last’ was released in 2006 and Anastacia has now gone done the fragrance route with her ‘Resurrection’ scent.

In 2007, Anastacia took part in the Princess Diana memorial concert - one of her first major appearances in two years. She performed as part of a medley, singing Superstar from the Andrew Lloyd Webber musical Jesus Christ Superstar.

The following year she released her fourth studio album 'Heavy Rotation'. Anastacia described it as a positive album, saying: 'It's been such a fast album I had no idea of what it was going to sound like, what I was going to say. I figured there would be a couple of love songs, but I didn't realise that most of the album was going to be as happy as it is.'

However, the album was not as successful commercially as her previous records.

In 2009, Anastacia teamed up with Lulu and Chaka Chan for the Here Come the Girls concert tour. The trio performed a rendition of Relight My Fire at the 2009 Royal Variety Performance.

Anastacia appeared as a guest judge during the 2012 series of The X Factor. She announced that her cancer had returned in 2013 when she cancelled her European tour. She underwent a double mastectomy. She released her album Resurrection the following year, which broke the top 10 on the UK charts. She released her first greatest hits album in 2015.